01289nas a2200169   4500000000100000008004100001260001600042653002100058100001300079700001500092245006500107856008800172300001400260490000800274520082300282022001401105       2022                            d  bElsevier BV10aGeneral Medicine1 aPieter Y1 aGrijsen ML00aPicturing health: the burden of leprosy in eastern Indonesia  uhttps://www.thelancet.com/journals/lancet/article/PIIS0140-6736(22)00699-7/fulltext  a1588-15990 v3993 a<p>Leprosy impacts impoverished communities in low-income and middle-income countries (LMICs), with over 200 000 new cases recorded annually worldwide. This infectious disease is caused by&nbsp;<em>Mycobacterium leprae</em>&nbsp;or&nbsp;<em>Mycobacterium lepromatosis</em>&nbsp;and primarily affects the skin and peripheral nerves. Effective multidrug therapy is available and, with early detection and treatment, leprosy is curable. Yet disease management can be complicated by immune-mediated reactions, which may cause irreversible nerve damage and lead to lifelong disabilities that are associated with stigmatisation and discrimination. Despite progress in the past few decades, the disease burden has stalled, with some countries not meeting WHO goals of interrupting transmission and reducing incidence.</p>
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