01809nas a2200265   4500000000100000008004100001260001200042653002300054653001200077653002300089653002600112653003800138100001700176700001500193700001500208700001300223700001700236700001500253245010100268856007000369300001200439490000600451520107200457022001401529       2022                            d  c05/202210aHansen’s disease10aleprosy10aLucio's phenomenon10aNecrotizing fasciitis10aNecrotizing soft tissue infection1 aBougioukli S1 aWilliams E1 aNwachuku I1 aSochol K1 aStevanovic M1 aLefebvre R00aNecrotizing Soft Tissue Infection of the Upper Extremity as a Manifestation of Hansen's Disease.  uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC9120760/pdf/main.pdf  a176-1800 v43 a<p>Hansen's disease is a well-described, largely historic infection that is caused by . Lucio's phenomenon is an aggressive, rare form of untreated lepromatous leprosy characterized by diffuse cutaneous lesions and systemic symptoms. To date, cases of necrotizing soft tissue infection in the setting of leprosy have rarely been reported in the literature. We present the case of a 51-year-old man with no known past medical history who presented for the evaluation of acute-on-chronic left upper extremity ulceration, soft tissue swelling, and pain. The patient was diagnosed with necrotizing soft tissue infection of the left upper extremity and underlying multibacillary lepromatous leprosy with Lucio's phenomenon. He underwent dermatofasciectomy of the affected extremity, followed by staged soft tissue coverage, including dermal allograft placement. Proper antibiotic management was also undertaken. In this article, we describe a case of previously undiagnosed leprosy with Lucio's phenomenon manifesting as necrotizing fasciitis of the upper extremity.</p>
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