01784nas a2200265   4500000000100000008004100001260001200042653001500054653001200069653002000081653001200101100001400113700001600127700001300143700001400156700001500170700001600185700001200201700001100213245005800224856006800282490000700350520114700357022001401504       2022                            d  c05/202210atratamento10aAnimals10aecoepidemiology10aleprosy1 ade Lima M1 aSilvestre M1 aSantos E1 aMartins L1 aQuaresma J1 ade Barros B1 aSilva M1 aLima L00aThe Presence of Mycobacterium leprae in Wild Rodents.  uhttps://www.mdpi.com/2076-2607/10/6/1114/pdf?version=16537257410 v103 a<p>Leprosy is a chronic infection caused by . There is a lack of data regarding environmental reservoirs, which may represent a serious public health problem in Brazil, especially in the state of Pará, which occupies the fourth position in incidence of cases in the country. Previous studies report evidence of infection occurring among armadillos, mangabei monkeys, and chimpanzees. In the present study, wild animals were captured and tested for the presence of anti-PGL-1 antibodies and DNA. Fieldwork was carried out from October to November of 2016 in the cities of Curionópolis and Canaã dos Carajás, southeast of Pará state. Small and medium-sized wild animals were captured using appropriate traps. A total of 15 animals were captured. Sera and viscera fragments were collected and tested by ELISA and PCR methods. The presence of DNA was confirmed by sequencing of specific gyrase gene in three animals of two different species, including one (liver sample) and two (kidney and liver samples). This unprecedented finding suggests that species other than those previously reported are responsible for maintaining in nature.</p>
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