01592nas a2200265   4500000000100000008004100001260001000042653001200052653002200064653003000086653002800116100001200144700001300156700001400169700001600183700001700199700001200216700001400228245006800242856005200310300001200362490000700374520093100381022001401312       2023                            d  bLepra10aLeprosy10aBuerger's disease10athromboangitis obliterans10avascular manifestations1 aBhatt S1 aPandey S1 aPaliwal G1 aVasudevan B1 aUday Bhanu K1 aNeema S1 aKothari R00aLeprosy with vascular involvement mimicking Buerger’s disease  uhttps://leprosyreview.org/article/94/2/20-22100  a169-1750 v943 a<p>Leprosy presenting with vascular involvement is very rare or is probably under-reported. Arteriographic and histopathological analysis has shown vascular involvement in few individuals with leprosy previously. It has also been found that vascular abnormality is central to the pathogenesis of trophic ulcer and nerve damage itself. A 37-year-old male presented to our center with pain, bluish discoloration and recurrent ulceration of digits of hands and feet of twelve months duration. Investigations revealed diminished caliber of the brachial artery with no other underlying abnormality. Dermatological review revealed features of primary neuritic leprosy confirmed by nerve biopsy and polymerase chain reaction (PCR) for&nbsp;Mycobacterium leprae&nbsp;positivity. This case highlights the fact that vascular involvement could rarely be a primary event in leprosy and cause Buerger’s disease-like manifestations.</p>
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