01876nas a2200217   4500000000100000008004100001653001500042653001600057653001900073653001200092653002500104100002300129700002000152700001400172700002000186245010700206856008100313300001400394490000700408520124300415       2023                            d10aborderline10aCase report10aHistopathology10aleprosy10aMycobacterium leprae1 aKarmila G. A. A. D1 aRusyati L. M. M1 aSaputra H1 aSari L. G. M. P00aBorderline type leprosy with variation of clinical manifestations and histopathology: two case reports  uhttps://balimedicaljournal.ejournals.ca/index.php/bmj/article/view/4572/2958  a2440-24450 v123 a<p><strong>Background:</strong>&nbsp;Leprosy is a chronic disease caused by&nbsp;<em>Mycobacterium leprae</em>. This disease can be diagnosed if one of the four criteria is met. Histopathological examination can vary depending on the spectrum of the disease. The following describes two cases of borderline-type leprosy that aimed to increase understanding of the diagnosis and management of leprosy, especially the borderline type.</p>

<p><strong>Cases:</strong>&nbsp;Both cases had complaints of numb spots on the body. The first case had more lesions than the second one with borderline-borderline histopathological examination results, while the second one had borderline lepromatous histopathological examination results. Both patients received the same therapy (multidrug therapy for multibacillary leprosy). During observation, there were no drug side effects that the patient could not tolerate. The prognosis in both cases is dubia, depending on the patient's adherence to treatment.&nbsp;</p>

<p><strong>Conclusion:</strong>&nbsp;The diversity of clinical and histopathological features can occur, including cases of leprosy. Early diagnosis and prompt treatment should be started as possible to prevent disabilities</p>