02543nas a2200265   4500000000100000008004100001260001200042653002000054653002500074653001200099653001900111653002200130100001300152700001300165700001200178700001200190700001100202700001200213245011300225856011100338300001200449490000700461520179500468022001402263       2023                            d  c01/202310aBacillary index10aMycobacterium leprae10aleprosy10aMultibacillary10aProspective study1 aGautam S1 aSharma D1 aSingh S1 aArora M1 aGoel A1 aBisht D00aAnalysis of socioeconomic condition and bacillary index with respect to the development of Hansen's disease.  uhttps://journals.lww.com/ijmy/fulltext/2023/12030/analysis_of_socioeconomic_condition_and_bacillary.6.aspx  a254-2600 v123 a<p><strong>Background: </strong>Leprosy is a chronic granulomatous infection caused by Mycobacterium leprae or Mycobacterium lepromatosis and mainly affects the skin and peripheral nerves. Although treatable, its early intervention can significantly reduce the occurrence of disability. India accounts for more than half of new cases globally. This study was undertaken to better understand the clinical traits of newly diagnosed cases in a tertiary facility of Western Uttar Pradesh, and a few from Madhya Pradesh and Uttarakhand.</p>

<p><strong>Methods: </strong>The observational prospective study was carried out on all the newly diagnosed leprosy cases who visited the Outpatient Department of ICMR-National JALMA Institute for Leprosy and Other Mycobacterial Diseases, Agra, during October 2019-December 2022. After obtaining answers to a prestructured questionnaire with their consent, participants were enrolled in the study and underwent clinical examination and a slit-skin smear test.</p>

<p><strong>Results: </strong>A total of 56 cases were investigated, and among them, 20 (35.7%) and 36 (64.3%) women and men, respectively, had positive contact with persons affected by leprosy either within family, friends, or neighbors. It is observed that due to the delayed detection of leprosy cases, paucibacillary (PB) patients converted into multibacillary (MB) patients, and the number of MB cases is much higher compared to PB cases.</p>

<p><strong>Conclusion: </strong>Leprosy instances continue to spread frequently from sick to healthy people indicating continued transmission of leprosy in society. Multidrug therapy in the management of leprosy cases is effective; however, early diagnosis of PB cases is still a challenge and needs to be addressed on priority.</p>
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