02144nas a2200421   4500000000100000008004100001260001200042653001400054653001700068653001800085653002700103653001300130653002500143653002300168653001700191653004000208653002800248653001300276100001500289700001500304700001700319700001200336700001400348700001100362700001000373700001300383700002000396700001400416700001300430700001400443700001200457245011000469856006100579300001400640490000700654520104700661022001401708       2023                            d  c10/202310aAustralia10aBuruli ulcer10aMycobacterium10aMycobacterium ulcerans10aBacteria10aCase-Control Studies10aProtective factors10aRisk Factors10aTuberculosis and other mycobacteria10aVector-borne infections10aZoonoses1 aMcNamara B1 aBlasdell K1 aYerramilli A1 aSmith I1 aClayton S1 aDunn M1 aTay E1 aGibney K1 aWaidyatillake N1 aHussain M1 aMuleme M1 aO'Brien D1 aAthan E00aComprehensive Case-Control Study of Protective and Risk Factors for Buruli Ulcer, Southeastern Australia.  uhttps://wwwnc.cdc.gov/eid/article/29/10/pdfs/23-0011.pdf  a2032-20430 v293 a<p>To examine protective and risk factors for Buruli ulcer (BU), we conducted a case-control study of 245 adult BU cases and 481 postcode-matched controls across BU-endemic areas of Victoria, Australia. We calculated age- and sex-adjusted odds ratios for socio-environmental, host, and behavioral factors associated with BU by using conditional logistic regression. Odds of BU were &gt;2-fold for persons with diabetes mellitus and persons working outdoors who had soil contact in BU-endemic areas (compared with indoor work) but were lower among persons who had bacillus Calmette-Guérin vaccinations. BU was associated with increasing numbers of possums and with ponds and bore water use at residences. Using insect repellent, covering arms and legs outdoors, and immediately washing wounds were protective; undertaking multiple protective behaviors was associated with the lowest odds of BU. Skin hygiene/protection behaviors and previous bacillus Calmette-Guérin vaccination might provide protection against BU in BU-endemic areas.</p>
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