01884nas a2200157   4500000000100000008004100001100001900042700002000061700001400081245004600095856006600141300001400207490000700221520148400228022001401712       2023                            d1 aHazlianda C. P1 aDalimunthe D. A1 aPartogi D00aAnalysis of vitamin E in leprosy patients  uhttps://www.jpad.com.pk/index.php/jpad/article/view/2334/2085  a1238-12410 v333 a<p><strong>Background:</strong>&nbsp;Mycobacterium leprae is the primary causative agent of the chronic infectious illness leprosy, can affect peripheral nerves and the skin. Vitamin E, a fat-soluble antioxidant, is essential in the body and can modulate various immune responses. Previous study showed reduced vitamin E levels in leprosy patients. This study evaluated vitamin E levels, differences in paucibacillary and multibacillary type leprosy subjects, and the correlation between bacterial index and vitamin E levels. &nbsp;</p>

<p><strong>Methods:</strong> In this study, 24 leprosy subjects have been included in this analytical investigation using a cross-sectional methodology. Between March and October 2018, the study was carried out in the Dermatology and Venerology Department of the Leprosy Division at the Haji Adam Malik General Hospital in Medan, Pirngadi General Hospital in Medan, Belidahan Leprosy Hospital, Sicanang Leprosy Hospital, and Lau Simomo Leprosy Hospital. &nbsp;</p>

<p><strong>Results:&nbsp;</strong>Leprosy was found primarily in males (70.8%), 16–35 years old (50%). The mean value of vitamin E levels in MB leprosy (9.62±3.91 mg/L) was lower than in PB leprosy (10.55±2.12 mg/L). This study showed a statistically significant correlation between bacterial index and vitamin E levels (r=0.284, p=0.043). &nbsp;</p>

<p><strong>Conclusion:</strong> There is a correlation between bacterial index and vitamin E levels. &nbsp;</p>
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