01952nas a2200229   4500000000100000008004100001260002000042653001200062653002200074653002000096100001500116700000600131700001200137700001200149700001300161245004500174856006400219300001200283490000700295520139500302022002501697       2018                            d  bKare Publishing10aLeprosy10aelectrocardiogram10aQT prolongation1 aYildirim E1 a 1 aSecen O1 aDemir B1 aBilen MN00aElectrocardiographic Findings of Leprosy  uhttps://jcpres.com/storage/upload/pdfs/EMJ_40_3_136_139.pdf  a136-1390 v403 a<p><strong>Objective: </strong>The purpose of the present study was to investigate the effect of leprosy on basic electrocardiography (ECG) parameters.</p>

<p><strong>Materials and Methods:</strong> A total of 66 patients including 33 patients with leprosy (mean age: 70.06 years, 24 males) and 33 control patients (mean age: 56.66 years, 15 males) were included in the study. ECG recordings of all patients were obtained, and groups were compared in terms of heart rate, PR, QT, QTc, JTc, and T peak to T end (Tp-e) durations and branch blocks.</p>

<p><strong>Results:</strong> QT (391.30 vs. 367.66, p&lt;0.01), QTc (423.57 vs. 407.15, p&lt;0.01), and Tp-e (74.18 vs. 66.93, p&lt;0.001) intervals were significantly prolonged in the leprosy group. The left anterior hemiblock (LAH) was observed more in patients with leprosy (42.4% in 14 patients) than in the non-leprosy group (42.4% vs. 12.1%, p&lt;0.01). In addition, the rate of the unifascicularblock was significantly higher in the leprosy group (39.4% vs. 9.1%, p&lt;0.01).</p>

<p><strong>Conclusion:</strong> Leprosy has a significant effect on QT, QTc, and Tp-e intervals. Prolongation of the QT, QTc, and Tp-e intervals is an indicator of leprosy's effect on the cardiac autonomic system. The ratio of the LAH is also rather high, and that may be a marker of the area where leprosy is most effective on the heart.</p>
  a2149-2247, 2149-2549