01233nas a2200169   4500000000100000008004100001653001200042653002500054653003100079100001300110700001300123245007100136856005200207300001000259490000600269520078800275       2020                            d10aleprosy10aMycobacterium leprae10aMycobacterium lepromatosis1 aAndrew K1 aKadala M00aLeprosy: A Review of History, Clinical Presentation and Treatments  uhttps://pubs.sciepub.com/ajidm/8/3/1/index.html  a88-940 v83 a<p>Leprosy is an ancient disease of mankind that has persisted for generations across various continents. The disease is caused by&nbsp;<em>Mycobacterium leprae</em>&nbsp;and&nbsp;<em>Mycobacterium lepromatosis</em>&nbsp;with humans acting as the natural reservoir. The transmission of Leprosy is still poorly understood, however it is widely accepted that the inhalation of aerosol droplets from cases with high mycobacterial loads is the most common mechanism. Leprosy affects the skin and peripheral nerves and has been a focus of a worldwide eradication campaign by the World Health Organisation which has been largely successful. Treatment is with the use of a multi drug therapy with Dapsone, Rifampicin and Clofazamin for 6 to 12 months depending on the type of leprosy.</p>