TY - JOUR
KW - Ecological studies
KW - Epidemiology
KW - leprosy
KW - Spatial analysis
KW - Time series studies
AU - Boigny R
AU - Cavalcante K
AU - Florencio C
AU - Nogueira P
AU - Gomes C
AU - Alencar C
AB - <p><strong>Background: </strong>To analyse the temporal trends and spatiotemporal distribution of leprosy relapse in Brazil from 2001 to 2021.</p>

<p><strong>Methods: </strong>An ecological study with a temporal trend approach and space-time analysis of leprosy relapse in Brazil was carried out with data from the Notifiable Diseases Information System.</p>

<p><strong>Results: </strong>A total of 31&nbsp;334 patients who experienced leprosy relapse were identified. The number of recurrent cases tended to increase throughout the study period, and this increase was significant among females and in almost all age groups, except for those &lt;15, 50-59 and ≥70&nbsp;y. Several clusters of high- and low-risk patients were identified across all regions with a heterogeneous distribution.</p>

<p><strong>Conclusions: </strong>The burden of relapse showed an increasing trend in some groups and was distributed in all regions.</p>

BT - Transactions of the Royal Society of Tropical Medicine and Hygiene
C1 - https://www.ncbi.nlm.nih.gov/pubmed/38708714
DA - 08/2024
DO - 10.1093/trstmh/trae021
IS - 8
J2 - Trans R Soc Trop Med Hyg
LA - ENG
M3 - Article
N2 - <p><strong>Background: </strong>To analyse the temporal trends and spatiotemporal distribution of leprosy relapse in Brazil from 2001 to 2021.</p>

<p><strong>Methods: </strong>An ecological study with a temporal trend approach and space-time analysis of leprosy relapse in Brazil was carried out with data from the Notifiable Diseases Information System.</p>

<p><strong>Results: </strong>A total of 31&nbsp;334 patients who experienced leprosy relapse were identified. The number of recurrent cases tended to increase throughout the study period, and this increase was significant among females and in almost all age groups, except for those &lt;15, 50-59 and ≥70&nbsp;y. Several clusters of high- and low-risk patients were identified across all regions with a heterogeneous distribution.</p>

<p><strong>Conclusions: </strong>The burden of relapse showed an increasing trend in some groups and was distributed in all regions.</p>

PY - 2024
SP - 537
EP - 549
T2 - Transactions of the Royal Society of Tropical Medicine and Hygiene
TI - Temporal trends and space-time distribution of leprosy relapse in Brazil from 2001 to 2021.
VL - 118
SN - 1878-3503
ER -