Hansen's disease (leprosy) is a rare infectious disease with less than 300 recorded cases in the United States every year. In this report, we present an 80-year-old White male with a three-year history of slowly progressive, pink, well-demarcated, and annular patches, plaques, and papules that started on his thighs and spread to his abdomen, chest, back, and upper extremities. After sequence identification on biopsies confirmed the diagnosis of leprosy, the patient was treated with an alternative regimen of monthly moxifloxacin, rifabutin, and minocycline. After a month of treatment, the patient reported a reduction in his rash. This report highlights a case of multibacillary leprosy in the southeastern United States. It is a very interesting study as the selection of this patient's treatment was complex, and he ultimately received an alternative therapeutic regimen. This case also highlights the rising incidence of leprosy in this region of the United States and stresses the importance of monitoring for warning signs indicative of this diagnosis to facilitate early treatment and attenuation of this disease.
BT - Cureus C1 - https://www.ncbi.nlm.nih.gov/pubmed/39238714 DA - 08/2024 DO - 10.7759/cureus.66275 IS - 8 J2 - Cureus LA - ENG M3 - Case Report N2 -Hansen's disease (leprosy) is a rare infectious disease with less than 300 recorded cases in the United States every year. In this report, we present an 80-year-old White male with a three-year history of slowly progressive, pink, well-demarcated, and annular patches, plaques, and papules that started on his thighs and spread to his abdomen, chest, back, and upper extremities. After sequence identification on biopsies confirmed the diagnosis of leprosy, the patient was treated with an alternative regimen of monthly moxifloxacin, rifabutin, and minocycline. After a month of treatment, the patient reported a reduction in his rash. This report highlights a case of multibacillary leprosy in the southeastern United States. It is a very interesting study as the selection of this patient's treatment was complex, and he ultimately received an alternative therapeutic regimen. This case also highlights the rising incidence of leprosy in this region of the United States and stresses the importance of monitoring for warning signs indicative of this diagnosis to facilitate early treatment and attenuation of this disease.
PY - 2024 T2 - Cureus TI - A Case of Multibacillary Borderline Lepromatous Leprosy in the United States Treated With Alternative Therapy. VL - 16 SN - 2168-8184 ER -