TY - JOUR KW - virchow cells KW - drug-induced pancytopenia KW - foamy histiocytes KW - fite-faraco stain KW - Pancytopenia KW - leprosy in bone marrow KW - mycobacterium leprae KW - lepromatous leprosy KW - bone marrow aspirate AU - Shine R AU - Amitkumar K AU - Ganapathy S AU - John JJ AU - Roy SG J AB -

Hansen’s disease is caused by Mycobacterium leprae. The clinical presentation of lepromatous leprosy is broad, affecting patients with reduced T-cell immune response and causing anergy. Usually, the patient presents with numerous red to brown nodules over the face and auricles and is diagnosed by skin biopsy. We hereby report an unusual case of a 40-year-old man who presented with altered sensorium and fever. Lepromatous leprosy was diagnosed initially in the bone marrow aspiration without any clinical suspicion or previous skin biopsy confirmation. Bone marrow infiltration by lepra bacilli is very rare, with only a few cases reported in the literature so far.

BT - Cureus DO - 10.7759/cureus.69223 LA - ENG M3 - Case Report N2 -

Hansen’s disease is caused by Mycobacterium leprae. The clinical presentation of lepromatous leprosy is broad, affecting patients with reduced T-cell immune response and causing anergy. Usually, the patient presents with numerous red to brown nodules over the face and auricles and is diagnosed by skin biopsy. We hereby report an unusual case of a 40-year-old man who presented with altered sensorium and fever. Lepromatous leprosy was diagnosed initially in the bone marrow aspiration without any clinical suspicion or previous skin biopsy confirmation. Bone marrow infiltration by lepra bacilli is very rare, with only a few cases reported in the literature so far.

PB - Springer Science and Business Media LLC PY - 2024 SP - 1 EP - 8 T2 - Cureus TI - A Rare Cause of Pancytopenia From Lepromatous Leprosy Diagnosed in Bone Marrow Aspiration: A Bolt From the Blue UR - https://assets.cureus.com/uploads/case_report/pdf/289528/20240912-110902-eh1ugl.pdf SN - 2168-8184 ER -