Background: Leprosy is a chronic granulomatous, infectious disease present in various clinicopathological forms. Histopathological examination of skin provides confirmatory diagnosis. Ridley and Jopling classification is used to classify leprosy. The objective of study was to identify the clinical pattern of leprosy and performed detail Clinico- histopathological correlation in our institute.
Method: The study was carried out on 85 skin biopsies received in between2021-2023 Biopsies were fixed in 10% formalin, processed, and stained with Haematoxylin and Eosin and Fite Faraco stain, examined and classified histopathologically according to RidleyJopling scale and then correlated with clinical diagnosis.
Result: The age of the patients was ranged from 0 to 89 years. The male to female ratio of patients was 3:1. Hypopigmented, hypoesthetic skin lesions were commonly seen.Majority of cases 28(32.9%) were in the age group of50 -59 years. Highest parity was observed in Lepromatous leprosy (69%). Maximum clinical and histopathological correlation between was observed in lepromatous type (69%) and Tuberculoid type (55.5%).
Conclusion: The clinical and histopathological features are useful in arriving definitive diagnosis and classification of the leprosy
BT - Journal of Cardiovascular Disease Research LA - ENG M3 - Article N2 -Background: Leprosy is a chronic granulomatous, infectious disease present in various clinicopathological forms. Histopathological examination of skin provides confirmatory diagnosis. Ridley and Jopling classification is used to classify leprosy. The objective of study was to identify the clinical pattern of leprosy and performed detail Clinico- histopathological correlation in our institute.
Method: The study was carried out on 85 skin biopsies received in between2021-2023 Biopsies were fixed in 10% formalin, processed, and stained with Haematoxylin and Eosin and Fite Faraco stain, examined and classified histopathologically according to RidleyJopling scale and then correlated with clinical diagnosis.
Result: The age of the patients was ranged from 0 to 89 years. The male to female ratio of patients was 3:1. Hypopigmented, hypoesthetic skin lesions were commonly seen.Majority of cases 28(32.9%) were in the age group of50 -59 years. Highest parity was observed in Lepromatous leprosy (69%). Maximum clinical and histopathological correlation between was observed in lepromatous type (69%) and Tuberculoid type (55.5%).
Conclusion: The clinical and histopathological features are useful in arriving definitive diagnosis and classification of the leprosy
PY - 2024 SP - 1 EP - 7 T2 - Journal of Cardiovascular Disease Research TI - Clinico-histological correlation of Hansen's disease at tertiary care centre UR - https://www.researchgate.net/profile/Prisha-Rishi/publication/384812067_Journal_of_Cardiovascular_Disease_Research_ORIGINAL_RESERCH_Clinico-histological_correlation_of_Hansen's_disease_at_tertiary_care_centre/links/67089952e3c0600c7c9b6273/Journal-of-Card ER -