TY - JOUR KW - Hansen disease KW - leprosy KW - Nonhealing ulcer KW - PRF KW - Platelet rich fibrin KW - Treatment KW - Trophic ulcer AU - Vendhan S AU - Neema S AU - Vasudevan B AU - Krishnan L AU - Gera V AB -

Autologous platelet-rich fibrin (PRF) therapy is beneficial in the treatment of nonhealing ulcers. We present a case series of nonhealing, trophic ulcers with underlying leprous neuropathy, treated successfully with PRF therapy. It was a prospective study, conducted in a tertiary care hospital in the western Maharashtra, India between April 2021 and March 2022. A total of 11 patients with 18 nonhealing trophic ulcers were included in the study and consisted of 8 men and 3 women. The patient's median age was 41 years (range, 33-68), the median size of the ulcers was 4 cm (range: 1-12 cm), the median duration of ulcers was 20 weeks (16-30 weeks), and time to heal after starting treatment was 4 weeks (range: 1-8 weeks). PRF is an easy-to-use, simple, safe, effective, and economical treatment for the management of trophic ulcers.

BT - Journal of cutaneous and aesthetic surgery C1 - https://www.ncbi.nlm.nih.gov/pubmed/39483664 DA - 01/2024 DO - 10.4103/JCAS.JCAS_192_22 IS - 3 J2 - J Cutan Aesthet Surg LA - ENG M3 - Article N2 -

Autologous platelet-rich fibrin (PRF) therapy is beneficial in the treatment of nonhealing ulcers. We present a case series of nonhealing, trophic ulcers with underlying leprous neuropathy, treated successfully with PRF therapy. It was a prospective study, conducted in a tertiary care hospital in the western Maharashtra, India between April 2021 and March 2022. A total of 11 patients with 18 nonhealing trophic ulcers were included in the study and consisted of 8 men and 3 women. The patient's median age was 41 years (range, 33-68), the median size of the ulcers was 4 cm (range: 1-12 cm), the median duration of ulcers was 20 weeks (16-30 weeks), and time to heal after starting treatment was 4 weeks (range: 1-8 weeks). PRF is an easy-to-use, simple, safe, effective, and economical treatment for the management of trophic ulcers.

PY - 2024 SP - 262 EP - 265 T2 - Journal of cutaneous and aesthetic surgery TI - Platelet-rich fibrin therapy in the management of nonhealing trophic ulcers due to underlying leprous neuropathy. UR - https://pmc.ncbi.nlm.nih.gov/articles/PMC11497549/pdf/JCAS-17-262.pdf VL - 17 SN - 0974-2077 ER -