TY - JOUR KW - CCL-2 KW - neuropathic pain KW - leprosy AU - Hanjaya H AU - Widyadharma IPE AU - Widyastuti K AB - Neuropathic pain is a debilitating symptom in leprosy patients that significantly impacts their quality of life. While the mechanisms underlying this pain remain unclear, recent research suggests a potential role for C-C motif chemokine ligand 2 (CCL-2), a chemokine involved in inflammatory processes. This literature review explores the association between CCL-2 levels and neuropathic pain in leprosy patients. We discuss the current understanding of CCL-2's role in nerve damage and inflammation, as well as its potential as a biomarker for predicting and monitoring neuropathic pain in leprosy. Understanding the role of CCL-2 in leprosy-associated neuropathic pain may lead to the development of novel therapeutic strategies and improve the management of this chronic condition. Keywords: CCL-2, neuropathic pain, leprosy BT - International Journal of Research and Review DO - 10.52403/ijrr.20241164 IS - 11 LA - ENG M3 - Article N2 - Neuropathic pain is a debilitating symptom in leprosy patients that significantly impacts their quality of life. While the mechanisms underlying this pain remain unclear, recent research suggests a potential role for C-C motif chemokine ligand 2 (CCL-2), a chemokine involved in inflammatory processes. This literature review explores the association between CCL-2 levels and neuropathic pain in leprosy patients. We discuss the current understanding of CCL-2's role in nerve damage and inflammation, as well as its potential as a biomarker for predicting and monitoring neuropathic pain in leprosy. Understanding the role of CCL-2 in leprosy-associated neuropathic pain may lead to the development of novel therapeutic strategies and improve the management of this chronic condition. Keywords: CCL-2, neuropathic pain, leprosy PB - Galore Knowledge Publication Pvt. Ltd. PY - 2024 SP - 620 EP - 627 T2 - International Journal of Research and Review TI - CCL-2 as a Potential Biomarker for Neuropathic Pain in Leprosy: A Literature Review UR - https://www.ijrrjournal.com/IJRR_Vol.11_Issue.11_Nov2024/IJRR64.pdf VL - 11 SN - 2349-9788, 2454-2237 ER -