Our patient presented with a 5-year history of chronic, asymptomatic papulonodular lesions on the extremities. The lesions spread to the face and earlobes, with new ulcerative lesions on both legs for the past 8 months. Skin biopsy was compatible with lepromatous leprosy with Lucio phenomenon. Lucio phenomenon is a rare type of leprosy reaction found mostly in neglected lepromatous leprosy cases. Unfortunately, the patient developed pulmonary embolism and passed away. This case report focuses on the clinicopathological characteristics and management of Lucio phenomenon, which is an unusual form of leprosy reaction that often carries a poorer prognosis. Importantly, physicians should be able to differentiate Lucio phenomenon from other types of leprosy reactions for prompt management.
BT - Dermatology Reports DO - 10.4081/dr.2025.10173 LA - ENG M3 - Case Report N2 -Our patient presented with a 5-year history of chronic, asymptomatic papulonodular lesions on the extremities. The lesions spread to the face and earlobes, with new ulcerative lesions on both legs for the past 8 months. Skin biopsy was compatible with lepromatous leprosy with Lucio phenomenon. Lucio phenomenon is a rare type of leprosy reaction found mostly in neglected lepromatous leprosy cases. Unfortunately, the patient developed pulmonary embolism and passed away. This case report focuses on the clinicopathological characteristics and management of Lucio phenomenon, which is an unusual form of leprosy reaction that often carries a poorer prognosis. Importantly, physicians should be able to differentiate Lucio phenomenon from other types of leprosy reactions for prompt management.
PB - PAGEPress Publications PY - 2025 EP - 9 T2 - Dermatology Reports TI - Lucio phenomenon: a case report on an overlooked reaction in lepromatous leprosy UR - https://www.pagepress.org/journals/dr/article/download/10173/9570 SN - 2036-7406, 2036-7392 ER -