TY - JOUR KW - Adolescent KW - Adult KW - Age Distribution KW - Cohort Studies KW - Drug Therapy, Combination KW - Female KW - Humans KW - Incidence KW - India KW - Leprostatic Agents KW - leprosy KW - Male KW - Middle Aged KW - Mycobacterium leprae KW - Peripheral nerves KW - Prospective Studies KW - Sex Distribution AU - Solomon S AU - Kurian N AU - Ramadas P AU - Rao P S AB -

The incidence rates of sensory and motor impairments during and after multidrug therapy (MDT) are reported for a prospective cohort of patients who had no nerve damage at registration (N = 1621). Sensory and motor loss increased with age and both were high among multibacillary patients as compared with paucibacillary patients. The lateral popliteal (common peroneal) and posterior tibial nerves seem to be most affected for sensory loss; whereas the posterior tibial and ulnar nerves are mainly responsible for motor loss. No significant difference by gender was found. Implications for prevention of disability (POD) activities are discussed and suitable recommendations made.

BT - International journal of leprosy and other mycobacterial diseases : official organ of the International Leprosy Association C1 - http://www.ncbi.nlm.nih.gov/pubmed/10347565?dopt=Abstract DA - 1998 Dec IS - 4 J2 - Int. J. Lepr. Other Mycobact. Dis. LA - eng N2 -

The incidence rates of sensory and motor impairments during and after multidrug therapy (MDT) are reported for a prospective cohort of patients who had no nerve damage at registration (N = 1621). Sensory and motor loss increased with age and both were high among multibacillary patients as compared with paucibacillary patients. The lateral popliteal (common peroneal) and posterior tibial nerves seem to be most affected for sensory loss; whereas the posterior tibial and ulnar nerves are mainly responsible for motor loss. No significant difference by gender was found. Implications for prevention of disability (POD) activities are discussed and suitable recommendations made.

PY - 1998 SP - 451 EP - 6 T2 - International journal of leprosy and other mycobacterial diseases : official organ of the International Leprosy Association TI - Incidence of nerve damage in leprosy patients treated with MDT. UR - http://ila.ilsl.br/pdfs/v66n4a02.pdf VL - 66 SN - 0148-916X ER -