TY - JOUR
KW - Adult
KW - Aged
KW - Animals
KW - Antibodies
KW - Female
KW - Fluorescent Antibody Technique
KW - Humans
KW - Leukocyte Count
KW - Male
KW - Mice
KW - Middle Aged
KW - Skin Diseases
KW - T-Lymphocytes
KW - T-Lymphocytes, Regulatory
AU - Fulton R
AU - Thivolet J
AU - Garcier F
AU - Gaucherand M
AB - <p>The total T lymphocyte and T cell subsets were counted in various dermatoses by indirect immunofluorescence using the monoclonal antibodies OKT3, OKT4, OKT8 which distinguish all peripheral T cells, helper T cells and suppressor T cells respectively. In particular, 7 cases of the Sézary syndrome and 7 cases of mycosis fungoides were studied. In addition, 42 other patients with diverse dermatoses such as psoriasis, atopic eczema, bullous disorders, sarcoidosis, lupus erythematosus and leprosy were studied and compared to 20 healthy controls. There was no significant increase in the total T cell percentage in the ratio of helper to suppressor lymphocytes in the Sézary syndrome with a normal balance in mycosis fungoides. Among the other dermatoses only atopic eczema showed a significant increase in the helper/suppressor ratio suggesting an imbalance of T cell subpopulations in this condition.</p>
BT - Annales de dermatologie et de venereologie
C1 - http://www.ncbi.nlm.nih.gov/pubmed/6455084?dopt=Abstract
DA - 1981
IS - 3
J2 - Ann Dermatol Venereol
LA - fre
N2 - <p>The total T lymphocyte and T cell subsets were counted in various dermatoses by indirect immunofluorescence using the monoclonal antibodies OKT3, OKT4, OKT8 which distinguish all peripheral T cells, helper T cells and suppressor T cells respectively. In particular, 7 cases of the Sézary syndrome and 7 cases of mycosis fungoides were studied. In addition, 42 other patients with diverse dermatoses such as psoriasis, atopic eczema, bullous disorders, sarcoidosis, lupus erythematosus and leprosy were studied and compared to 20 healthy controls. There was no significant increase in the total T cell percentage in the ratio of helper to suppressor lymphocytes in the Sézary syndrome with a normal balance in mycosis fungoides. Among the other dermatoses only atopic eczema showed a significant increase in the helper/suppressor ratio suggesting an imbalance of T cell subpopulations in this condition.</p>
PY - 1981
SP - 243
EP - 6
SP - 249
EP - 50
T2 - Annales de dermatologie et de venereologie
TI - [Sub-populations of T helper suppressor lymphocytes in diverse dermatoses using monoclonal antibodies. Preliminary results (author's transl)].
VL - 108
SN - 0151-9638
ER -