TY - JOUR KW - Antigens KW - BCG Vaccine KW - DNA KW - Humans KW - leprosy KW - Skin Tests KW - Tuberculosis AU - Sinha S AU - Sengupta U AU - Ramu G AU - Desikan K V AB -

Leprosy patients were skin tested for induction of skin delayed type hypersensitivity (DTH) with various preparations of Dharmendra Antigen (DA) (sonicated antigen, DNA + RNA and DNA). Extracted nucleic acids produced smaller reactions (including some negative ones) as compared to sonicated whole antigen (which included proteins). BCG fractions, prepared similarly, produced non specific skin reactions.

BT - Leprosy in India C1 - http://www.ncbi.nlm.nih.gov/pubmed/7132292?dopt=Abstract CN - Infolep Library - available DA - 1982 Apr IS - 2 J2 - Lepr India LA - eng N2 -

Leprosy patients were skin tested for induction of skin delayed type hypersensitivity (DTH) with various preparations of Dharmendra Antigen (DA) (sonicated antigen, DNA + RNA and DNA). Extracted nucleic acids produced smaller reactions (including some negative ones) as compared to sonicated whole antigen (which included proteins). BCG fractions, prepared similarly, produced non specific skin reactions.

PY - 1982 SP - 214 EP - 9 T2 - Leprosy in India TI - Assessment of Dharmendra antigen. (VI) skin tests with fractionated nucleic acids. VL - 54 SN - 0024-1024 ER -