TY - JOUR
KW - Adult
KW - Animals
KW - Antimony Sodium Gluconate
KW - Antiprotozoal Agents
KW - Diagnosis, Differential
KW - Female
KW - Humans
KW - Leishmania donovani
KW - Leishmaniasis, Cutaneous
KW - Leishmaniasis, Visceral
KW - leprosy
KW - Male
AU - Dhar S
AU - Kaur I
AU - Dawn G
AU - Sehgal S
AU - Kumar B
AB - <p>We report on 4 cases of post-kala-azar dermal leishmaniasis (PKDL). History of kala-azar was available in all 4 patients. Slit-skin smears (SSS) for leishmania donovani (LD) bodies were negative in all 4. In 3 patients hypopigmented lesions were present over the face. Papules and nodules over his lips, tongue, scrotum and dactylitis were some unusual features observed in 1 patient. Histopathological examination showed LD bodies in 2 patients; histopathology was nonspecific in the other 2. All the patients were treated with sodium stibogluconate, 20 mg/kg/day. Infiltrated papules and nodules had subsided by 3 months, while hypopigmented macules took longer to improve. In 3 patients there had previously been a misdiagnosis as leprosy sufferers and they had been treated with antileprosy drugs. Clinical and histopathological differences between PKDL and leprosy are discussed.</p>
BT - Leprosy review
C1 - http://www.ncbi.nlm.nih.gov/pubmed/7500822?dopt=Abstract
CN - Infolep Library - available
DA - 1995 Sep
DO - 10.5935/0305-7518.19950029
IS - 3
J2 - Lepr Rev
LA - eng
N2 - <p>We report on 4 cases of post-kala-azar dermal leishmaniasis (PKDL). History of kala-azar was available in all 4 patients. Slit-skin smears (SSS) for leishmania donovani (LD) bodies were negative in all 4. In 3 patients hypopigmented lesions were present over the face. Papules and nodules over his lips, tongue, scrotum and dactylitis were some unusual features observed in 1 patient. Histopathological examination showed LD bodies in 2 patients; histopathology was nonspecific in the other 2. All the patients were treated with sodium stibogluconate, 20 mg/kg/day. Infiltrated papules and nodules had subsided by 3 months, while hypopigmented macules took longer to improve. In 3 patients there had previously been a misdiagnosis as leprosy sufferers and they had been treated with antileprosy drugs. Clinical and histopathological differences between PKDL and leprosy are discussed.</p>
PY - 1995
SP - 250
EP - 6
T2 - Leprosy review
TI - Post-kala-azar dermal leishmaniasis mimicking leprosy: experience with 4 patients, with some unusual features in 1.
UR - http://leprev.ilsl.br/pdfs/1995/v66n3/pdf/v66n3a10.pdf
VL - 66
SN - 0305-7518
ER -