TY - JOUR
KW - Adolescent
KW - Adult
KW - BCG Vaccine
KW - Case-Control Studies
KW - Child
KW - Child, Preschool
KW - Female
KW - Humans
KW - Infant
KW - Infant, Newborn
KW - Male
KW - Odds Ratio
KW - Risk
KW - Socioeconomic Factors
KW - Tuberculosis
AU - Zodpey S P
AU - Maldhure B R
AU - Dehankar A G
AU - Shrikhande S N
AB - <p>A hospital-based pair-matched case-control study was carried out at Govt. Medical College Hospital, Nagpur, to estimate the effectiveness of BCG vaccination against extra-pulmonary tuberculosis. The study included 125 cases of extra-pulmonary tuberculosis in the age group of 0-30 years and 375 tuberculosis free control. Each case was pair matched against three separate controls for age, sex and socioeconomic status. The protective effectiveness and prevented fraction were higher for the subjects in the age group of 0-10 years, males and subjects from middle and upper strata of socio-economic class but it was statistically nonsignificant. The overall vaccine effectiveness and prevented fraction was estimated to be 80.86 (72.68-86.60) and 53.20 (41.97-63.73) per cent respectively. Results of this study thus indicated that BCG vaccination was highly effective against extra-pulmonary tuberculosis and played a significant role in its prevention in this population.</p>
BT - The Journal of communicable diseases
C1 - http://www.ncbi.nlm.nih.gov/pubmed/8810141?dopt=Abstract
DA - 1996 Jun
IS - 2
J2 - J Commun Dis
LA - eng
N2 - <p>A hospital-based pair-matched case-control study was carried out at Govt. Medical College Hospital, Nagpur, to estimate the effectiveness of BCG vaccination against extra-pulmonary tuberculosis. The study included 125 cases of extra-pulmonary tuberculosis in the age group of 0-30 years and 375 tuberculosis free control. Each case was pair matched against three separate controls for age, sex and socioeconomic status. The protective effectiveness and prevented fraction were higher for the subjects in the age group of 0-10 years, males and subjects from middle and upper strata of socio-economic class but it was statistically nonsignificant. The overall vaccine effectiveness and prevented fraction was estimated to be 80.86 (72.68-86.60) and 53.20 (41.97-63.73) per cent respectively. Results of this study thus indicated that BCG vaccination was highly effective against extra-pulmonary tuberculosis and played a significant role in its prevention in this population.</p>
PY - 1996
SP - 77
EP - 84
T2 - The Journal of communicable diseases
TI - Effectiveness of bacillus Calmette Guerin (BCG) vaccination against extra-pulmonary tuberculosis: a case-control study.
VL - 28
SN - 0019-5138
ER -