TY - JOUR KW - Adolescent KW - Adult KW - Aged KW - Brazil KW - Child KW - Child, Preschool KW - Disease Notification KW - Endemic Diseases KW - Female KW - Humans KW - leprosy KW - Male KW - Middle Aged KW - Models, Statistical KW - Prevalence KW - Space-Time Clustering KW - Young Adult AU - Rodrigues-Júnior AL AU - O VT AU - Motti VG AB -

OBJECTIVE: To assess the temporal and spatial evolution of the leprosy endemy in the state of São Paulo, Southeastern Brazil.

METHODS: This is an ecological-social study that used the number of leprosy cases reported to the Brazilian Ministry of Health from January 2004 to December 2006. Monthly series were generated in each regional health department, and their sequences were adjusted by a Markovian model for the leprosy detection coefficients. The detection coefficient with the number of cases accumulated in the period in each municipality was used to produce the spatial distribution of the endemy; a correlation analysis was carried out with the leprosy detection coefficients and the components of the Social Responsibility Index of the state of São Paulo.

RESULTS: Of the 645 municipalities of the state of São Paulo, 22 did not detect leprosy cases in the period. In the majority of regions, the endemy showed a decreasing trend; the time series presented random fluctuation around expected values. The decline was influenced by a generalized decrease in the detection coefficients at the end of 2005. There was a positive correlation between the detection coefficients and the components "schooling" and "longevity", of the Social Responsibility Index of the state of São Paulo, and a negative correlation with "wealth", another component of the same Index.

CONCLUSIONS: The result of the time series analysis suggests that the endemy is on the decline in the majority of regions of the state of São Paulo, while the spatial analysis shows that the coefficients are high in the northern part of the state.

BT - Revista de saude publica C1 - http://www.ncbi.nlm.nih.gov/pubmed/19009159?dopt=Abstract DA - 2008 Dec DO - 10.1590/s0034-89102008000600006 IS - 6 J2 - Rev Saude Publica LA - eng N2 -

OBJECTIVE: To assess the temporal and spatial evolution of the leprosy endemy in the state of São Paulo, Southeastern Brazil.

METHODS: This is an ecological-social study that used the number of leprosy cases reported to the Brazilian Ministry of Health from January 2004 to December 2006. Monthly series were generated in each regional health department, and their sequences were adjusted by a Markovian model for the leprosy detection coefficients. The detection coefficient with the number of cases accumulated in the period in each municipality was used to produce the spatial distribution of the endemy; a correlation analysis was carried out with the leprosy detection coefficients and the components of the Social Responsibility Index of the state of São Paulo.

RESULTS: Of the 645 municipalities of the state of São Paulo, 22 did not detect leprosy cases in the period. In the majority of regions, the endemy showed a decreasing trend; the time series presented random fluctuation around expected values. The decline was influenced by a generalized decrease in the detection coefficients at the end of 2005. There was a positive correlation between the detection coefficients and the components "schooling" and "longevity", of the Social Responsibility Index of the state of São Paulo, and a negative correlation with "wealth", another component of the same Index.

CONCLUSIONS: The result of the time series analysis suggests that the endemy is on the decline in the majority of regions of the state of São Paulo, while the spatial analysis shows that the coefficients are high in the northern part of the state.

PY - 2008 SP - 1012 EP - 20 T2 - Revista de saude publica TI - Spatial and temporal study of leprosy in the state of São Paulo (Southeastern Brazil), 2004-2006. TT - Estudio espacial y temporal de la hanseníasis en Sao Paulo (Sureste de Brasil), 2004-2006 UR - http://www.scielosp.org/pdf/rsp/v42n6/en_6768.pdf VL - 42 SN - 1518-8787 ER -