TY - JOUR
KW - Antimetabolites, Antineoplastic
KW - Cell Transformation, Neoplastic
KW - Deoxycytidine
KW - Diagnostic Errors
KW - Disease Progression
KW - Granuloma
KW - Humans
KW - leprosy
KW - Magnetic Resonance Imaging
KW - Male
KW - Middle Aged
KW - Muscle Weakness
KW - Mycosis Fungoides
KW - Skin Neoplasms
KW - Treatment Outcome
AU - Siriphukpong S
AU - Pattanaprichakul P
AU - Sitthinamsuwan P
AU - Karoopongse E
AB - <p><b>BACKGROUND: </b>Granulomatous mycosis fungoides is an unusual histopathological variant of cutaneous T-cell lymphoma without clinical distinction from classic mycosis fungoides. Symptoms associated with peripheral nerve involvement have rarely been reported in the literature.</p><p><b>CASE REPORT: </b>The authors described a case of granulomatous MF stage IIB with large cell transformation who initially presented with leprosy-like condition and chronic left peroneal neuropathy The patient received six courses ofgemcitabine with greater than 90% improvement of skin lesions. The rest of the lesions were successfully treated with local electron beam radiation.</p><p><b>CONCLUSION: </b>Granulomatous MF with neuropathy can be clinically misdiagnosed if there is no histopathological and immunohistochemical finding to support the diagnosis of lymphoma.</p>
BT - Journal of the Medical Association of Thailand = Chotmaihet thangphaet
C1 - http://www.ncbi.nlm.nih.gov/pubmed/21114213?dopt=Abstract
C6 - Article in pdf format
DA - 2010 Nov
IS - 11
J2 - J Med Assoc Thai
LA - eng
N2 - <p><b>BACKGROUND: </b>Granulomatous mycosis fungoides is an unusual histopathological variant of cutaneous T-cell lymphoma without clinical distinction from classic mycosis fungoides. Symptoms associated with peripheral nerve involvement have rarely been reported in the literature.</p><p><b>CASE REPORT: </b>The authors described a case of granulomatous MF stage IIB with large cell transformation who initially presented with leprosy-like condition and chronic left peroneal neuropathy The patient received six courses ofgemcitabine with greater than 90% improvement of skin lesions. The rest of the lesions were successfully treated with local electron beam radiation.</p><p><b>CONCLUSION: </b>Granulomatous MF with neuropathy can be clinically misdiagnosed if there is no histopathological and immunohistochemical finding to support the diagnosis of lymphoma.</p>
PY - 2010
SP - 1321
EP - 6
T2 - Journal of the Medical Association of Thailand = Chotmaihet thangphaet
TI - Granulomatous mycosis fungoides with large cell transformation misdiagnosed as leprosy.
UR - http://www.mat.or.th/journal/files/Vol93_No.11_1321_6270.pdf
VL - 93
SN - 0125-2208
ER -