Han et al. have made a retrospective isolation of DNA from two patients with fatal Lucio's phenomenon. This DNA does have some molecular differences to M. leprae and may constitute a variant of M. leprae. However the experiments and data needed to confirm that this is a new leprosy-causing species have not yet been done. We have outlined the work that does need to be done. For the moment the assertion that 'M. lepromatosis' is a new leprosy-causing species is not proven.
BT - Leprosy review C1 - http://www.ncbi.nlm.nih.gov/pubmed/22125927?dopt=Abstract C2 - UK CY - Colchester DA - 2011 Sep IS - 3 J2 - Lepr Rev LA - eng N2 -Han et al. have made a retrospective isolation of DNA from two patients with fatal Lucio's phenomenon. This DNA does have some molecular differences to M. leprae and may constitute a variant of M. leprae. However the experiments and data needed to confirm that this is a new leprosy-causing species have not yet been done. We have outlined the work that does need to be done. For the moment the assertion that 'M. lepromatosis' is a new leprosy-causing species is not proven.
PB - LEPRA Health in Action PP - Colchester PY - 2011 SP - 205 EP - 9 T2 - Leprosy review TI - What is the evidence that the putative Mycobacterium lepromatosis species causes diffuse lepromatous leprosy? UR - https://leprosyreview.org/article/82/3/01-702 VL - 82 SN - 0305-7518 ER -