Dapsone, a potent antiparasitic and anti-inflammatory compound, is mainly used in the treatment of leprosy and a variety of blistering skin diseases. It may cause a severe adverse drug reaction with multiorgan involvement known as dapsone hypersensitivity syndrome. We report an unusual case of dapsone hypersensitivity, manifesting as bone marrow suppression and peripheral pancytopenia in addition to fever, rash, and hepatosplenomegaly.
BT - Indian dermatology online journal C1 - http://www.ncbi.nlm.nih.gov/pubmed/23130233?dopt=Abstract DA - 2011 Jul DO - 10.4103/2229-5178.85999 IS - 2 J2 - Indian Dermatol Online J LA - eng N2 -Dapsone, a potent antiparasitic and anti-inflammatory compound, is mainly used in the treatment of leprosy and a variety of blistering skin diseases. It may cause a severe adverse drug reaction with multiorgan involvement known as dapsone hypersensitivity syndrome. We report an unusual case of dapsone hypersensitivity, manifesting as bone marrow suppression and peripheral pancytopenia in addition to fever, rash, and hepatosplenomegaly.
PY - 2011 SP - 88 EP - 90 T2 - Indian dermatology online journal TI - An unusual case of dapsone syndrome. UR - http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3481807/ VL - 2 SN - 2249-5673 ER -