TY - JOUR AU - Desvignes L AU - Ernst JD AB -

In a recent Science paper, Teles et al. (2013) show that type I and II interferons (IFNs) are reciprocally expressed in the polar immune forms of leprosy, with type I IFNs inducing IL-10 that interferes with the antimycobacterial effects of type II IFNs (IFNγ) at the site of infection.

BT - Cell host & microbe C1 - http://www.ncbi.nlm.nih.gov/pubmed/23601100?dopt=Abstract CN - DESVIGNES 2013 DA - 2013 Apr 17 DO - 10.1016/j.chom.2013.04.001 IS - 4 J2 - Cell Host Microbe LA - eng N2 -

In a recent Science paper, Teles et al. (2013) show that type I and II interferons (IFNs) are reciprocally expressed in the polar immune forms of leprosy, with type I IFNs inducing IL-10 that interferes with the antimycobacterial effects of type II IFNs (IFNγ) at the site of infection.

PY - 2013 SP - 377 EP - 8 T2 - Cell host & microbe TI - Taking sides: interferons in leprosy. VL - 13 SN - 1934-6069 ER -