Leprosy is a chronic infectious disease caused by Mycobacterium leprae, a microorganism that usually affects skin and nerves. Although it is usually well-controlled by multidrug therapy (MDT), the disease may be aggravated by acute inflammatory reaction episodes that cause permanent tissue damage particularly to peripheral nerves. Tuberculosis is predominantly a disease of the lungs; however, it may spread to other organs and cause an extrapulmonary infection. Both mycobacterial infections are endemic in developing countries including Brazil, and cases of coinfection have been reported in the last decade. Nevertheless, simultaneous occurrence of perianal cutaneous tuberculosis and erythema nodosum leprosum is very rare, even in countries where both mycobacterial infections are endemic.
BT - The journal of venomous animals and toxins including tropical diseases C1 - http://www.ncbi.nlm.nih.gov/pubmed/25180030?dopt=Abstract DO - 10.1186/1678-9199-20-38 J2 - J Venom Anim Toxins Incl Trop Dis LA - eng N2 -Leprosy is a chronic infectious disease caused by Mycobacterium leprae, a microorganism that usually affects skin and nerves. Although it is usually well-controlled by multidrug therapy (MDT), the disease may be aggravated by acute inflammatory reaction episodes that cause permanent tissue damage particularly to peripheral nerves. Tuberculosis is predominantly a disease of the lungs; however, it may spread to other organs and cause an extrapulmonary infection. Both mycobacterial infections are endemic in developing countries including Brazil, and cases of coinfection have been reported in the last decade. Nevertheless, simultaneous occurrence of perianal cutaneous tuberculosis and erythema nodosum leprosum is very rare, even in countries where both mycobacterial infections are endemic.
PY - 2014 EP - 38 T2 - The journal of venomous animals and toxins including tropical diseases TI - Lepromatous leprosy and perianal tuberculosis: a case report and literature review. UR - http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4150118/pdf/1678-9199-20-38.pdf VL - 20 SN - 1678-9199 ER -