Pupil abnormalities in leprosy usually result from chronic iritis with loss of stroma, iris miosis, a sluggish reaction to light, and poor dilation in response to anticholinergic mydriatics. We report two patients with long-standing lepromatous leprosy who developed tonic pupils characterized by mydriasis, absence of reaction to light and hypersensitivity to weak cholinergic solution. Examination revealed iritis and iris atrophy. In both cases, instillation of dilute 0.1% pilocarpine caused miosis in the affected eyes. Tonic pupil occurs in many conditions, but its association with leprosy had not been previously reported.
BT - Arquivos brasileiros de oftalmologia C1 -http://www.ncbi.nlm.nih.gov/pubmed/25627189?dopt=Abstract
DO - 10.5935/0004-2749.20140098 IS - 6 J2 - Arq Bras Oftalmol LA - eng N2 -Pupil abnormalities in leprosy usually result from chronic iritis with loss of stroma, iris miosis, a sluggish reaction to light, and poor dilation in response to anticholinergic mydriatics. We report two patients with long-standing lepromatous leprosy who developed tonic pupils characterized by mydriasis, absence of reaction to light and hypersensitivity to weak cholinergic solution. Examination revealed iritis and iris atrophy. In both cases, instillation of dilute 0.1% pilocarpine caused miosis in the affected eyes. Tonic pupil occurs in many conditions, but its association with leprosy had not been previously reported.
PY - 2014 SP - 395 EP - 6 T2 - Arquivos brasileiros de oftalmologia TI - Tonic pupil in leprosy. TT - Pupila tônica em doença de Hansen UR - http://www.scielo.br/pdf/abo/v77n6/0004-2749-abo-77-06-0395.pdf VL - 77 SN - 1678-2925 ER -