Blood donors' samples (1007) were assessed for anti-PGL-1 IgM antibodies and Mycobacterium leprae DNA presence, with 3.8% and 0.3% positivity, respectively. After a five-year follow-up period, six individuals with positive markers developed leprosy, raising the hypothesis that asymptomatic infection among blood donors may be an undisclosed mode of leprosy transmission via transfusion.
BT - Journal of clinical microbiology C1 -http://www.ncbi.nlm.nih.gov/pubmed/26202111?dopt=Abstract
DO - 10.1128/JCM.01305-15 IS - Jul 22 J2 - J. Clin. Microbiol. LA - eng N2 -Blood donors' samples (1007) were assessed for anti-PGL-1 IgM antibodies and Mycobacterium leprae DNA presence, with 3.8% and 0.3% positivity, respectively. After a five-year follow-up period, six individuals with positive markers developed leprosy, raising the hypothesis that asymptomatic infection among blood donors may be an undisclosed mode of leprosy transmission via transfusion.
PB - © American Society for Microbiology PY - 2015 EP - [Epub ahead of print] T2 - Journal of clinical microbiology TI - Asymptomatic leprosy infection among blood donors may predict disease development and suggests a potential mode of transmission. UR - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4572540/pdf/zjm3345.pdf SN - 1098-660X ER -