Five of 10 paucibacillary leprosy patients were Quantiferon Gold positive with negative chest x-rays. Forty multibacillary leprosy patients were Quantiferon Gold(Q-G) negative. Reports have shown 100% cross reactivity of ESAT6 and CFP10 between M. leprae and M. tb. The Q-G gold test cannot detect latent TB in patients with leprosy.
BT - Clinical infectious diseases : an official publication of the Infectious Diseases Society of America C1 -http://www.ncbi.nlm.nih.gov/pubmed/26209684?dopt=Abstract
DO - 10.1093/cid/civ588 IS - Jul 24 J2 - Clin. Infect. Dis. LA - eng N2 -Five of 10 paucibacillary leprosy patients were Quantiferon Gold positive with negative chest x-rays. Forty multibacillary leprosy patients were Quantiferon Gold(Q-G) negative. Reports have shown 100% cross reactivity of ESAT6 and CFP10 between M. leprae and M. tb. The Q-G gold test cannot detect latent TB in patients with leprosy.
PB - Oxford Journals PY - 2015 EP - [Epub ahead of print] T2 - Clinical infectious diseases : an official publication of the Infectious Diseases Society of America TI - Quantiferon-Gold TB Cannot Detect Latent TB in Patients with Leprosy. SN - 1537-6591 ER -