TY - JOUR
KW - Toxin
KW - Neglected tropical diseases (NTDs)
KW - Mycolactone A/B
KW - Exotoxin
KW - Buruli ulcer
AU - Saint-Auret S
AU - Chany A
AU - Casarotto V
AU - Tresse C
AU - Parmentier L
AU - Abdelkafi H
AU - Blanchard N
AB - <p>Buruli ulcer, classified as a neglected tropical disease by the World Health Organization, is caused by a mycobacterium which secretes a macrolidic exotoxin called mycolactone A/B. In this article, several synthetic strategies for the preparation of this toxin are discussed, highlighting the importance of total synthesis for the exploration of biological mechanism underpinning relevant human diseases.</p>

BT - Chimia
C1 - <p>http://www.ncbi.nlm.nih.gov/pubmed/29289244?dopt=Abstract</p>

DO - 10.2533/chimia.2017.836
IS - 12
J2 - Chimia (Aarau)
LA - eng
N2 - <p>Buruli ulcer, classified as a neglected tropical disease by the World Health Organization, is caused by a mycobacterium which secretes a macrolidic exotoxin called mycolactone A/B. In this article, several synthetic strategies for the preparation of this toxin are discussed, highlighting the importance of total synthesis for the exploration of biological mechanism underpinning relevant human diseases.</p>

PY - 2017
SP - 836
EP - 840
T2 - Chimia
TI - Total syntheses of mycolactone A/B and its analogues for the exploration of the biology of Buruli ulcer.
VL - 71
SN - 0009-4293
ER -