TY - JOUR KW - Risk Factors KW - Retrospective Studies KW - Nervous System Diseases KW - leprosy KW - Leprostatic Agents KW - Humans KW - Disease Progression KW - Disabled Persons KW - Disability Evaluation KW - Brazil AU - Costa L AU - Cortela D AU - Soares RCFR AU - Ignotti E AB -

OBJECTIVES: To analyse factors associated with the worsening of physical disabilities during the treatment of leprosy in Brazil in cases that were newly diagnosed in 2009.

METHODS: This epidemiological study performed as a retrospective cohort investigated the factors associated with the worsening of the physical disability grade during the treatment of paucibacillary and multibacillary leprosy cases. Logistic regression with a confidence interval of 95% was used to analyse the variables associated with the worsening of disability grade.

RESULTS: The cases with the greatest odds for worsening physical disability grade were patients from the south (odds ratio [OR] = 2.60) and southeast regions (OR = 1.74); with multibacillary disease (OR = 3.48); who were illiterate (OR = 2.26); and with reactive episodes (OR = 2.42).

CONCLUSIONS: The factors associated with higher odds of worsening physical disability during treatment demonstrate failure to apply appropriate remedial measures to prevent disabilities, and greater attention should be given to patients with the most severe disease.

BT - Leprosy review C1 -

http://www.ncbi.nlm.nih.gov/pubmed/26665362?dopt=Abstract

IS - 3 J2 - Lepr Rev LA - eng N2 -

OBJECTIVES: To analyse factors associated with the worsening of physical disabilities during the treatment of leprosy in Brazil in cases that were newly diagnosed in 2009.

METHODS: This epidemiological study performed as a retrospective cohort investigated the factors associated with the worsening of the physical disability grade during the treatment of paucibacillary and multibacillary leprosy cases. Logistic regression with a confidence interval of 95% was used to analyse the variables associated with the worsening of disability grade.

RESULTS: The cases with the greatest odds for worsening physical disability grade were patients from the south (odds ratio [OR] = 2.60) and southeast regions (OR = 1.74); with multibacillary disease (OR = 3.48); who were illiterate (OR = 2.26); and with reactive episodes (OR = 2.42).

CONCLUSIONS: The factors associated with higher odds of worsening physical disability during treatment demonstrate failure to apply appropriate remedial measures to prevent disabilities, and greater attention should be given to patients with the most severe disease.

PY - 2015 SP - 265 EP - 72 T2 - Leprosy review TI - Factors associated with the worsening of the disability grade during leprosy treatment in Brazil. UR - https://leprosyreview.org/article/86/3/26-5272 VL - 86 SN - 0305-7518 ER -