TY - JOUR KW - Brazil KW - Epidemiology KW - leprosy KW - Mortality KW - Spatial analysis AU - Souza EA AU - Nzundu Boigny R AU - Oliveira HX AU - Oliveira MLWD AU - Heukelbach J AU - Alencar C AU - Martins-Melo FR AU - Novaes Ramos A AB -

Background
Leprosy is a neglected condition with a high mortality burden, especially in poorer areas. The objective of this study was to analyze temporal trends and spatiotemporal patterns of mortality related to leprosy in the state of Bahia, 1999-2014.

Objective
To analyze the spatiotemporal trends and patterns of mortality associated with leprosy in the state of Bahia, Brazil, from 1999 to 2014.

Method
Population-based study utilizing secondary mortality data including all deaths, in which leprosy was mentioned, recorded in the state of Bahia from 1999 to 2014.

Results
From a total of 1,152,262 deaths, leprosy was identified in 481 (0.04%) cases, resulting in a mean annual gross mortality rate of 0.21 deaths/100,000 inhabitants (95% confidence interval [CI]: 0.13-0.29). Unspecified leprosy (87.73%; 422/481) and leprosy complications (6.44%; 31/484) were the most commonly reported clinical forms. Risk of death associated with leprosy was higher among men (relative risk [RR]: 2.38; 95% CI; 0.19-0.46), elderly (RR: 74.79; 95% CI; 9.57-582.20), and in the eastern region of the state (RR: 4.08; 95% CI; 2.33-7.15). Overall mortality rates showed a significant increase during the observation period (Average Annual Percentage Change [AAPC] 7.3, 95% CI; 4.5-10.3), as well as proportional mortality (AAPC 5.3; 95% CI; 2.2-8.3).

Conclusions
Leprosy is a neglected cause of death in the state of Bahia. The disease presents unequal regional spatiotemporal trends, with risks associated mainly in males and older age groups.

BT - Cadernos saúde coletiva DO - 10.1590/1414-462x201800020255 IS - 2 J2 - Cad Saude Colet LA - eng, por N2 -

Background
Leprosy is a neglected condition with a high mortality burden, especially in poorer areas. The objective of this study was to analyze temporal trends and spatiotemporal patterns of mortality related to leprosy in the state of Bahia, 1999-2014.

Objective
To analyze the spatiotemporal trends and patterns of mortality associated with leprosy in the state of Bahia, Brazil, from 1999 to 2014.

Method
Population-based study utilizing secondary mortality data including all deaths, in which leprosy was mentioned, recorded in the state of Bahia from 1999 to 2014.

Results
From a total of 1,152,262 deaths, leprosy was identified in 481 (0.04%) cases, resulting in a mean annual gross mortality rate of 0.21 deaths/100,000 inhabitants (95% confidence interval [CI]: 0.13-0.29). Unspecified leprosy (87.73%; 422/481) and leprosy complications (6.44%; 31/484) were the most commonly reported clinical forms. Risk of death associated with leprosy was higher among men (relative risk [RR]: 2.38; 95% CI; 0.19-0.46), elderly (RR: 74.79; 95% CI; 9.57-582.20), and in the eastern region of the state (RR: 4.08; 95% CI; 2.33-7.15). Overall mortality rates showed a significant increase during the observation period (Average Annual Percentage Change [AAPC] 7.3, 95% CI; 4.5-10.3), as well as proportional mortality (AAPC 5.3; 95% CI; 2.2-8.3).

Conclusions
Leprosy is a neglected cause of death in the state of Bahia. The disease presents unequal regional spatiotemporal trends, with risks associated mainly in males and older age groups.

PY - 2018 SP - 191 EP - 202 T2 - Cadernos saúde coletiva TI - [Spatiotemporal patterns of leprosy-related mortality in Bahia state, northeastern Brazil, 1999-2014] TT - Tendências e padrões espaço-temporais da mortalidade relacionada à hanseníase no Estado da Bahia, Nordeste do Brasil, 1999-2014 UR - http://www.scielo.br/pdf/cadsc/v26n2/1414-462X-cadsc-26-2-191.pdf VL - 26 SN - 1414-462X ER -