TY - JOUR KW - leprosy KW - Dapsone KW - Sulfone Syndrome AU - Gonçalves TS AU - Pereira ECG AU - Netto PRS AU - Freire RAC AU - Mendes SUR AB -

We report the case of a woman with leprosy who was treated with MDT-MB/ WHO and presented 4 weeks after the start of treatment, fever, malaise, weakness, jaundice, edema and rashes in feet and hands, hepatitis, pruritus, dysphagia, haemolytic anemia, submandibular lymph node, as well as nausea, vomiting and epigastric pain. Laboratory tests showed decreased hemoglobin, leukocytosis, eosinophilia, increased hepatic transaminases, indirect hyperbilirubinemia, hypoalbuminemia, DHL and elevated TAP. A diagnosis of Dapsone Syndrome was established, treatment of leprosy was suspended and the patient was advised to return treatment after hospital discharge, with replacement of dapsone.

BT - Revista de Patologia do Tocantins IS - 4 LA - por, eng N2 -

We report the case of a woman with leprosy who was treated with MDT-MB/ WHO and presented 4 weeks after the start of treatment, fever, malaise, weakness, jaundice, edema and rashes in feet and hands, hepatitis, pruritus, dysphagia, haemolytic anemia, submandibular lymph node, as well as nausea, vomiting and epigastric pain. Laboratory tests showed decreased hemoglobin, leukocytosis, eosinophilia, increased hepatic transaminases, indirect hyperbilirubinemia, hypoalbuminemia, DHL and elevated TAP. A diagnosis of Dapsone Syndrome was established, treatment of leprosy was suspended and the patient was advised to return treatment after hospital discharge, with replacement of dapsone.

PY - 2018 SP - 28 EP - 31 T2 - Revista de Patologia do Tocantins TI - [Case report: Sulfone Syndrome in leprosy patient] TT - Relato de caso: Síndrome da Sulfona em paciente com hanseníase UR - http://scholar.google.nl/scholar_url?url=https://sistemas.uft.edu.br/periodicos/index.php/patologia/article/download/5071/14513&hl=nl&sa=X&d=13403405165673474039&scisig=AAGBfm2P00zIuSxYRbZTyyMswQqxytX2aA&nossl=1&oi=scholaralrt&hist=732gnZIAAAAJ:1269093288 VL - 5 ER -