An ultrastructural study of peripheral nerves in leprosy patients was carried out of ascertain the changes in Schwann cells containing myelinated and nonmyelinated axons. Axonal multiplication was noticed in nonmyelinated axons in specimens from both tuberculoid and lepromatous leprosy. The Schwann cells in tuberculoid nerves were devoid of M. leprae in contrast to those in lepromatous nerves in which large number of bacilli were seen. These observations suggest that the Schwann cells containing nonmyelinated axons may be affected more frequently in either type of leprosy.
BT - Indian journal of leprosy C1 - http://www.ncbi.nlm.nih.gov/pubmed/1573304?dopt=Abstract CN - Infolep Library - available DA - 1992 Jan-Mar IS - 1 J2 - Indian J Lepr LA - eng N2 -An ultrastructural study of peripheral nerves in leprosy patients was carried out of ascertain the changes in Schwann cells containing myelinated and nonmyelinated axons. Axonal multiplication was noticed in nonmyelinated axons in specimens from both tuberculoid and lepromatous leprosy. The Schwann cells in tuberculoid nerves were devoid of M. leprae in contrast to those in lepromatous nerves in which large number of bacilli were seen. These observations suggest that the Schwann cells containing nonmyelinated axons may be affected more frequently in either type of leprosy.
PY - 1992 SP - 81 EP - 7 T2 - Indian journal of leprosy TI - An ultrastructural study of Schwann cells in peripheral nerves of leprosy patients. VL - 64 SN - 0254-9395 ER -