TY - JOUR KW - Animals KW - DNA, Bacterial KW - Female KW - Infectious Disease Incubation Period KW - leprosy KW - Mycobacterium leprae KW - Pan troglodytes KW - Polymorphism, Single Nucleotide KW - Primate Diseases KW - Sequence Analysis, DNA AU - Suzuki K AU - Udono T AU - Fujisawa M AU - Tanigawa K AU - Idani G AU - Ishii N AB -

The length of the incubation period of leprosy following Mycobacterium leprae infection has never been conclusively determined, owing to the lack of a method to demonstrate the presence of an asymptomatic infection. We report a rare case of leprosy in a chimpanzee in which a 30-year incubation period was strongly suggested by single nucleotide polymorphism (SNP) analysis.

BT - Journal of clinical microbiology C1 - http://www.ncbi.nlm.nih.gov/pubmed/20631101?dopt=Abstract DA - 2010 Sep DO - 10.1128/JCM.00017-10 IS - 9 J2 - J. Clin. Microbiol. LA - eng N2 -

The length of the incubation period of leprosy following Mycobacterium leprae infection has never been conclusively determined, owing to the lack of a method to demonstrate the presence of an asymptomatic infection. We report a rare case of leprosy in a chimpanzee in which a 30-year incubation period was strongly suggested by single nucleotide polymorphism (SNP) analysis.

PY - 2010 SP - 3432 EP - 4 T2 - Journal of clinical microbiology TI - Infection during infancy and long incubation period of leprosy suggested in a case of a chimpanzee used for medical research. UR - http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2937736/pdf/0017-10.pdf VL - 48 SN - 1098-660X ER -