TY - JOUR
KW - 3K1
KW - Mycobacterium leprae
KW - Philippines
KW - Saudi Arabia
KW - antimicrobial resistance
KW - bacteria
KW - biopsy
KW - drug resistance
KW - imported infectious diseases
KW - indels
KW - leprosy
KW - metagenomics
KW - rpoB
KW - rrs
KW - single-nucleotide polymorphisms
KW - tuberculosis and other mycobacteria
AU - Guan Q
AU - Almutairi T
AU - Alhalouli T
AU - Pain A
AU - Alasmari F
AB - <p>Using shotgun metagenomics, we identified an imported case of multidrug-resistant Mycobacterium leprae in a Filipino resident of Saudi Arabia in 2017. We determined the phylogenomic lineage (3K1) and identified mutations in rpoB and rrs corresponding to the multidrug-resistance phenotype clinically observed. Metagenomics sequencing can be used to identify multidrug-resistant M. leprae.</p>
BT - Emerging infectious diseases
C1 - https://www.ncbi.nlm.nih.gov/pubmed/32091380
DA - 03/2020
DO - 10.3201/eid2603.190661
IS - 3
J2 - Emerging Infect. Dis.
LA - eng
N2 - <p>Using shotgun metagenomics, we identified an imported case of multidrug-resistant Mycobacterium leprae in a Filipino resident of Saudi Arabia in 2017. We determined the phylogenomic lineage (3K1) and identified mutations in rpoB and rrs corresponding to the multidrug-resistance phenotype clinically observed. Metagenomics sequencing can be used to identify multidrug-resistant M. leprae.</p>
PY - 2020
SP - 615
EP - 617
T2 - Emerging infectious diseases
TI - Metagenomics of Imported Multidrug-Resistant Mycobacterium leprae, Saudi Arabia, 2017.
UR - https://wwwnc.cdc.gov/eid/article/26/3/19-0661_article
VL - 26
SN - 1080-6059
ER -