TY - JOUR
KW - HLA
KW - HLA-G
KW - Immune response
KW - leprosy
AU - da Silva C
AU - Sampaio L
AU - Costa MB
AU - Cysneiros M
AU - Sadissou I
AU - Castilho M
AU - de Moraes J
AU - Donadi E
AU - Wastoswki I
AB - <p>The aim of this study was to evaluate the expression of human leukocyte antigen G (HLA-G) in leprosy. Biopsy and serum samples were collected from 18 patients presenting with leprosy and from healthy controls. Samples were analyzed using immunohistochemistry and ELISA techniques. HLA-G expression was observed in biopsy samples of all patients. The healthy control samples were consistently negative for HLA-G expression. Control plasma samples displayed significantly higher HLA-G expression than those from the patients (p < 0.01). These results are the first demonstration of the expression of HLA-G in leprosy.</p>
BT - Immunogenetics
C1 - https://www.ncbi.nlm.nih.gov/pubmed/32556498
DA - 06/2020
DO - 10.1007/s00251-020-01168-4
J2 - Immunogenetics
LA - eng
N2 - <p>The aim of this study was to evaluate the expression of human leukocyte antigen G (HLA-G) in leprosy. Biopsy and serum samples were collected from 18 patients presenting with leprosy and from healthy controls. Samples were analyzed using immunohistochemistry and ELISA techniques. HLA-G expression was observed in biopsy samples of all patients. The healthy control samples were consistently negative for HLA-G expression. Control plasma samples displayed significantly higher HLA-G expression than those from the patients (p < 0.01). These results are the first demonstration of the expression of HLA-G in leprosy.</p>
PY - 2020
T2 - Immunogenetics
TI - Analysis of HLA-G protein expression in leprosy.
SN - 1432-1211
ER -