TY - JOUR
KW - leprosy
KW - non-neuropathic
KW - non-trophic
KW - pseudoepitheliomatous hyperplasia
KW - ulcer
KW - ulcerated Sweet syndrome-like erythema nodosum leprosum
AU - Shukla P
AU - Malhotra K
AU - Verma P
AU - Suvirya S
AU - Saraswat A
AU - Jain A
AB - <p>Non-neuropathic ulcers in leprosy patients are infrequently seen, and atypical presentations are prone to misdiagnosis. We evaluated diagnosed cases of leprosy between January 2017 and January 2020 for the presence of cutaneous ulceration, Ridley-Jopling subtype of leprosy, reactions and histologic features of these ulcerations. Treatment was given as WHO recommended multi-bacillary multi-drug therapy. We found 17/386 leprosy patients with non-neuropathic ulcers. We describe three causes - spontaneous cutaneous ulceration in lepromatous leprosy (one nodular and one diffuse), lepra reactions (five patients with type 1; nine with type 2, further categorised into ulcerated Sweet syndrome-like who also had pseudoepitheliomatous hyperplasia, pustulo-necrotic and necrotic erythema nodosum leprosum) and Lucio phenomenon (one patient). Our series draws attention towards the different faces of non-neuropathic ulcers in leprosy, including some atypical and novel presentations.</p>
BT - Tropical doctor
C1 - https://www.ncbi.nlm.nih.gov/pubmed/33722150
DA - 03/2021
DO - 10.1177/0049475521998499
J2 - Trop Doct
LA - eng
N2 - <p>Non-neuropathic ulcers in leprosy patients are infrequently seen, and atypical presentations are prone to misdiagnosis. We evaluated diagnosed cases of leprosy between January 2017 and January 2020 for the presence of cutaneous ulceration, Ridley-Jopling subtype of leprosy, reactions and histologic features of these ulcerations. Treatment was given as WHO recommended multi-bacillary multi-drug therapy. We found 17/386 leprosy patients with non-neuropathic ulcers. We describe three causes - spontaneous cutaneous ulceration in lepromatous leprosy (one nodular and one diffuse), lepra reactions (five patients with type 1; nine with type 2, further categorised into ulcerated Sweet syndrome-like who also had pseudoepitheliomatous hyperplasia, pustulo-necrotic and necrotic erythema nodosum leprosum) and Lucio phenomenon (one patient). Our series draws attention towards the different faces of non-neuropathic ulcers in leprosy, including some atypical and novel presentations.</p>
PY - 2021
EP - 49475521998499
T2 - Tropical doctor
TI - Unusual non-trophic ulcerations in leprosy: A case series of 17 patients.
SN - 1758-1133
ER -