TY - JOUR
KW - Leprosy
KW - anti-M. Leprae
KW - IgM antibodies
AU - Lema T
AU - Bobosha K
AU - Kasang C
AU - van Hooij A
AU - Mengiste A
AU - Geluk A
AU - Aseffa 
AU - Woldeamanuel Y
AB - <p>As part of a study that aimed at reaching those at risk of developing leprosy through screening of household contacts, a child aged 7 was included as contact of a multibacillary leprosy patient. This study was conducted in Kokosa, hot spot area in Oromia Region, Ethiopia. Compared to other contacts, this child showed increased levels of anti-M. leprae Phenolic glycolipid-I (PGL-I) IgM antibodies as assessed by up-converting lateral flow assay (UCP -LFA) at initial and second-time screening and developed leprosy three years later. Therefore, the anti-PGL-I IgM UCP-LFA can serve as an additional diagnostic field tool in leprosy control programs.</p>

BT - Ethiopian Medical Journal
IS - 3
LA - Eng
M3 - Case report
N2 - <p>As part of a study that aimed at reaching those at risk of developing leprosy through screening of household contacts, a child aged 7 was included as contact of a multibacillary leprosy patient. This study was conducted in Kokosa, hot spot area in Oromia Region, Ethiopia. Compared to other contacts, this child showed increased levels of anti-M. leprae Phenolic glycolipid-I (PGL-I) IgM antibodies as assessed by up-converting lateral flow assay (UCP -LFA) at initial and second-time screening and developed leprosy three years later. Therefore, the anti-PGL-I IgM UCP-LFA can serve as an additional diagnostic field tool in leprosy control programs.</p>

PY - 2023
SP - 293
EP - 295
T2 - Ethiopian Medical Journal
TI - Increased anti-M. Leprae PGL-I igm levels in a child who developed leprosy
UR - https://www.ajol.info/index.php/emj/article/view/252306/238370
VL - 60
SN - 2415-2420
ER -