This chapter discusses possible mechanisms of nerve damage during infection with Mycobacterium leprae. It examines the damage caused by immunological as well as by physical factors. It looks at the nerve damage in patients with Morbus Hansen and in their contacts. It discusses the damage caused by reactions in Hansen’s disease, Type 1, and Type 2 (Reversal Reaction and Erythema Nodosum Leprosum). Autoimmunity is suggested as a possible driving force for reactions.
BT - Hansen’s Disease DO - 10.1007/978-3-031-30893-2_12 N2 -This chapter discusses possible mechanisms of nerve damage during infection with Mycobacterium leprae. It examines the damage caused by immunological as well as by physical factors. It looks at the nerve damage in patients with Morbus Hansen and in their contacts. It discusses the damage caused by reactions in Hansen’s disease, Type 1, and Type 2 (Reversal Reaction and Erythema Nodosum Leprosum). Autoimmunity is suggested as a possible driving force for reactions.
PB - Springer International Publishing PY - 2023 SN - 9783031308925 SP - 139 EP - 145 T2 - Hansen’s Disease TI - Neuropathophysiology in Morbus Hansen or Hansen’s Disease: Mechanisms of Nerve Injury ER -