The preference of Mycobacterium leprae for Schwann cells leads to neural impairment by leprosy, which is responsible for the occurrence of sequelae and disabilities resulting from the disease. The involvement of peripheral nerves by Hansen’s disease can be detectable even in the absence of skin lesions in the early stages of the disease, and during the chronic course, manifesting late or abruptly during the inflammatory episodes represented by hansenic reactions. Knowing the main subsequent clinical changes is essential to minimize the consequences and disabilities resulting from this fact.
BT - Hansen’s Disease DO - 10.1007/978-3-031-30893-2_13 LA - Eng N2 -The preference of Mycobacterium leprae for Schwann cells leads to neural impairment by leprosy, which is responsible for the occurrence of sequelae and disabilities resulting from the disease. The involvement of peripheral nerves by Hansen’s disease can be detectable even in the absence of skin lesions in the early stages of the disease, and during the chronic course, manifesting late or abruptly during the inflammatory episodes represented by hansenic reactions. Knowing the main subsequent clinical changes is essential to minimize the consequences and disabilities resulting from this fact.
PB - Springer International Publishing PY - 2023 SN - 9783031308925 SP - 147 EP - 165 T2 - Hansen’s Disease TI - Neurological Alterations In Hansen’s Disease ER -