TY - JOUR
KW - Mycobacterium leprae
KW - Cattle
KW - leprosy
KW - reservoir
KW - ticks
KW - Transmission
KW - Vector
AU - Krausser L
AU - Chauvaux E
AU - Van Dyck-Lippens M
AU - Yssouf A
AU - Assoumani Y
AU - Tortosa P
AU - de Jong B
AU - Braet S
AB - <p><strong>Introduction: </strong>Leprosy, one of the oldest known human diseases, continues to pose a global challenge for disease control due to an incomplete understanding of its transmission pathways. Ticks have been proposed as a potential contributor in leprosy transmission due to their importance as vectors for other infectious diseases.</p>

<p><strong>Methods: </strong>In 2010, a sampling of ticks residing on cattle was conducted on the islands Grande Comore, Anjouan, and Mohéli which constitute the Union of the Comoros where leprosy remains endemic. To investigate the potential role of ticks as a vector in transmission of leprosy disease, molecular analyses were conducted.</p>

<p><strong>Results: </strong>Out of the 526 ticks analysed, none were found to harbour DNA, as determined by a quantitative polymerase chain reaction (qPCR) assay targeting a family of dispersed repeats (RLEP) specific to .</p>

<p><strong>Discussion: </strong>Therefore, our results suggest that in the Union of the Comoros, ticks are an unlikely vector for .</p>

BT - Frontiers in medicine
C1 - <p>https://www.ncbi.nlm.nih.gov/pubmed/37859857</p>

DA - 01/2023
DO - 10.3389/fmed.2023.1238914
J2 - Front Med (Lausanne)
LA - eng
N2 - <p><strong>Introduction: </strong>Leprosy, one of the oldest known human diseases, continues to pose a global challenge for disease control due to an incomplete understanding of its transmission pathways. Ticks have been proposed as a potential contributor in leprosy transmission due to their importance as vectors for other infectious diseases.</p>

<p><strong>Methods: </strong>In 2010, a sampling of ticks residing on cattle was conducted on the islands Grande Comore, Anjouan, and Mohéli which constitute the Union of the Comoros where leprosy remains endemic. To investigate the potential role of ticks as a vector in transmission of leprosy disease, molecular analyses were conducted.</p>

<p><strong>Results: </strong>Out of the 526 ticks analysed, none were found to harbour DNA, as determined by a quantitative polymerase chain reaction (qPCR) assay targeting a family of dispersed repeats (RLEP) specific to .</p>

<p><strong>Discussion: </strong>Therefore, our results suggest that in the Union of the Comoros, ticks are an unlikely vector for .</p>

PY - 2023
SP - 1
EP - 5
T2 - Frontiers in medicine
TI - Ticks are unlikely to play a role in leprosy transmission in the Comoros (East Africa) as they do not harbour  DNA.
UR - https://www.frontiersin.org/articles/10.3389/fmed.2023.1238914/pdf?isPublishedV2=False
VL - 10
SN - 2296-858X
ER -