Objective: The purpose of the present study was to investigate the effect of leprosy on basic electrocardiography (ECG) parameters.
Materials and Methods: A total of 66 patients including 33 patients with leprosy (mean age: 70.06 years, 24 males) and 33 control patients (mean age: 56.66 years, 15 males) were included in the study. ECG recordings of all patients were obtained, and groups were compared in terms of heart rate, PR, QT, QTc, JTc, and T peak to T end (Tp-e) durations and branch blocks.
Results: QT (391.30 vs. 367.66, p<0.01), QTc (423.57 vs. 407.15, p<0.01), and Tp-e (74.18 vs. 66.93, p<0.001) intervals were significantly prolonged in the leprosy group. The left anterior hemiblock (LAH) was observed more in patients with leprosy (42.4% in 14 patients) than in the non-leprosy group (42.4% vs. 12.1%, p<0.01). In addition, the rate of the unifascicularblock was significantly higher in the leprosy group (39.4% vs. 9.1%, p<0.01).
Conclusion: Leprosy has a significant effect on QT, QTc, and Tp-e intervals. Prolongation of the QT, QTc, and Tp-e intervals is an indicator of leprosy's effect on the cardiac autonomic system. The ratio of the LAH is also rather high, and that may be a marker of the area where leprosy is most effective on the heart.
BT - Erciyes Tıp Dergisi/Erciyes Medical Journal DO - 10.5152/etd.2017.0158 IS - 3 LA - Eng N2 -Objective: The purpose of the present study was to investigate the effect of leprosy on basic electrocardiography (ECG) parameters.
Materials and Methods: A total of 66 patients including 33 patients with leprosy (mean age: 70.06 years, 24 males) and 33 control patients (mean age: 56.66 years, 15 males) were included in the study. ECG recordings of all patients were obtained, and groups were compared in terms of heart rate, PR, QT, QTc, JTc, and T peak to T end (Tp-e) durations and branch blocks.
Results: QT (391.30 vs. 367.66, p<0.01), QTc (423.57 vs. 407.15, p<0.01), and Tp-e (74.18 vs. 66.93, p<0.001) intervals were significantly prolonged in the leprosy group. The left anterior hemiblock (LAH) was observed more in patients with leprosy (42.4% in 14 patients) than in the non-leprosy group (42.4% vs. 12.1%, p<0.01). In addition, the rate of the unifascicularblock was significantly higher in the leprosy group (39.4% vs. 9.1%, p<0.01).
Conclusion: Leprosy has a significant effect on QT, QTc, and Tp-e intervals. Prolongation of the QT, QTc, and Tp-e intervals is an indicator of leprosy's effect on the cardiac autonomic system. The ratio of the LAH is also rather high, and that may be a marker of the area where leprosy is most effective on the heart.
PB - Kare Publishing PY - 2018 SP - 136 EP - 139 T2 - Erciyes Tıp Dergisi/Erciyes Medical Journal TI - Electrocardiographic Findings of Leprosy UR - https://jcpres.com/storage/upload/pdfs/EMJ_40_3_136_139.pdf VL - 40 SN - 2149-2247, 2149-2549 ER -