01740nas a2200241 4500000000100000008004100001653001200042653002200054653001600076653002000092100001100112700001200123700001200135700001100147700001000158700001000168245010200178856005800280300000700338490000600345520113300351022001401484 2018 d10aleprosy10aNerve enlargement10aneuratrophy10aUltrasonography1 aChen X1 aZhang L1 aHuang M1 aZhai X1 aWen Y1 aPan C00aCoexistence of Nerve Enlargement and Neuratrophy Detected by Ultrasonography in Leprosy Patients. uhttp://www.nature.com/articles/s41598-018-26085-1.pdf a110 v83 a

The purpose of this study was to evaluate peripheral neural impairment in leprosy patients by ultrasonography (US). The cross-sectional areas (CSAs) of the median (M), ulnar (U) and common fibular (CF) nerves were compared in 71 leprosy patients and 29 healthy controls, and the data were analyzed between the leprosy, multibacillary (MB)/paucibacillary (PB), reaction (R)/no reaction (NR), disability (D)/no disability (ND), and longer/shorter duration groups after treatment. We found that for the nerves located in upper limbs, the CSAs were significantly increased in the leprosy patients vs the controls; the PB group vs the MB group; the R group vs the NR group; the ND group vs the D group; and the longer duration group vs the shorter duration group at some positions of the M nerve and U nerve. In contrast, for the nerves located in lower limbs, the CSAs were significantly reduced in the leprosy patients vs the controls and in the longer duration group vs the shorter duration group at some positions of the CF nerve. This result indicated that nerve enlargement and neuratrophy coexist in leprosy patients.

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