Autologous Subcutaneous Platelet-Rich Plasma in the Management of Non- Healing Trophic Ulcer in Leprosy

Trophic ulcers in leprosy patients are one of the commonest causes of disability and deformity. The management of trophic ulcers poses a great challenge to the dermatologists/ surgeons/ leprologists and the search for more effective therapeutic management continues. Platelet-rich Plasma (PRP) has been found to accelerate skin wound healing and promote re-epithelialization and its role in the management of chronic leg ulcer has been reported with satisfactory results. We report two cases of non-healing trophic ulcers in leprosy patients treated with subcutaneous PRP that had shown poor response to conventional treatment and showed improvement with subcutaneous PRP injections.